Crawley manager Steve Evans has defensive issues as Glenn Wilson (hamstring) and Karl Broadhurst (back) are doubts.
Midfielder Thomas Pinault is likely to start despite an ongoing back problem.
Crawley boss Steve Evans told BBC Sussex:
"We go up there and we have to come back with something. We cannot just allow those top five or six to slip away from us.
"Wrexham are going to pass and move for fun and they've got some gifted players as we know as well. It's a different type of game to last week."
Source: BBC Sport
Source: BBC Sport